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. 2021 May 18;11:652312. doi: 10.3389/fonc.2021.652312

Table 4.

Univariate analysis of overall survival in all patients.

Variables OS
HR (95% CI) P value
Gender (Male vs Female) 0.730 (0.387-1.379) 0.332
Age (<60 vs ≥60) 0.624 (0.355-1.096) 0.101
Histology (Squamous NSCLC vs Non-squamous NSCLC vs Small cell lung cancer) 1.213 (0.576-2.554) 0.612
Smoking status (Never vs Former or current) 1.385 (0.387-1.379) 0.025*
PD-L1 expression (<1% vs ≥1% vs NA) 1.206 (0.620-2.343) 0.581
SUVmax 1.059 (1.005-1.117) 0.033*
SUVmaxwb 1.010 (0.998-1.022) 0.119
SUVpeak 1.030 (0.975-1.089) 0.293
SUVmean 1.077 (0.920-1.261) 0.357
SUVmeanwb 0.998 (0.881-1.131) 0.981
MTV 1.000 (0.997-1.002) 0.864
MTVwb 0.999 (0.881-1.131) 0.486
TLG 1.000 (0.998-1.003) 0.987
TLGwb 1.000 (0.999-1.000) 0.906
LDH,U/L 1.003 (1.000-1.005) 0.049*
Absolute platelet count,×109/L 0.999 (0.996-1.003) 0.660
Absolute neutrophil count,×109/L 0.968 (0.850-1.103) 0.628
Albumin levels, g/L 0.968 (0.900-1.040) 0.374
dNLR 0.974 (0.791-1.199) 0.803

HR, hazard ratio; NSCLC non‒small-cell lung cancer; PD-L1, programmed death ligand 1, was acquired by immunohistochemistry; NA, not available; SUVmax maximum standardized uptake value; SUVpeak peak standardized uptake value; SUVmean mean standardized uptake value; MTV metabolic tumor volume; TLG total lesion glycolysis; SUVmaxwb whole-body maximum standardized uptake value; SUVmeanwb whole-body mean standardized uptake value; MTVwb, whole-body metabolic tumor volume; TLGwb, whole-body total lesion glycolysis; LDH lactate dehydrogenase; dNLR was defined as absolute neutrophil count/[white blood cell concentration − absolute neutrophil count]; OS, overall survival;* p<0.05.