Skip to main content
. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Gastrointest Endosc Clin N Am. 2021 Jul;31(3):503–517. doi: 10.1016/j.giec.2021.03.005

Table 2:

Guidelines Issued by United States Professional Societies

Society Year Recommendation
Gastric Cancer Screening
American Society of Gastrointestinal Endoscopy70 2015 Endoscopic screening for gastric cancer in first-generation immigrants from high-risk regions (e.g. Japan, China, Russia, and South America) may be considered for those aged 40 years, particularly if there is a family history of gastric cancer in a first-degree relative
Surveillance of Intestinal Metaplasia (IM)
American Society of Gastrointestinal Endoscopy14, 70 2015 Endoscopic surveillance in patients with gastric atrophic gastritis or IM coupled with an increased risk of gastric cancer because of racial/ethnic background, extensive anatomic distribution, or family history
American Gastroenterological Association71 2019 Recommends against routine use of endoscopic surveillance in patients with IM. Conditional recommendation, very low quality of evidence

Patients with IM at higher risk for gastric cancer who put a high value on potential but uncertain reduction in gastric cancer mortality, and who put a low value on potential risks of surveillance endoscopies, may reasonably elect for surveillance.

Patients with IM specifically at higher risk of gastric cancer include those with:
  • Incomplete vs complete IM

  • Extensive vs limited IM

  • Family history of gastric cancer



Patients at overall increased risk for gastric cancer include:
  • Racial/ethnic minorities

  • Immigrants from high incidence regions

Existing recommendations from United States-based professional societies regarding screening of gastric cancer or surveillance of precancerous lesions such as intestinal metaplasia (IM).