Table 1.
Demographic and clinical characteristics at the time of ART initiation among PWH from CCASAnet sites
| All Sites Except Haitia | Haiti | |
|---|---|---|
| N=13,197 | N=17,491 | |
| Country, n (%) | ||
| Argentina | 548 (4·2) | |
| Brazil | 3,327 (25·2) | |
| Chile | 2,584 (19·6) | |
| Honduras | 1027 (7·8) | |
| Mexico | 1,177 (8·9) | |
| Peru | 4,534 (34·4) | |
| Age at ART initiation in years, median (IQR) | 34·3 (28·0–42·3) | 37·2 (30·1–45·4) |
| Sex, n (%) | ||
| Female | 3,086 (23·4) | 10,250 (58·6) |
| Male | 10,111 (76·6) | 7,241 (41·4) |
| HIV Transmission Risk Factor, n (%) | ||
| Heterosexual women | 2,765 (21·0) | |
| Heterosexual men | 3,067 (23·2) | |
| Men who have sex with men | 6,296 (47·7) | |
| Injection drug use | 55 (0·4) | |
| Other or unknown | 1014 (7·7) | |
| Education, n (%) | ||
| Lower Secondary and Below | 2,895 (21·9) | 7,739 (44·2) |
| Upper Secondary and Above | 8,784 (66·5) | 6,550 (37·5) |
| Other or missing | 1,518 (11·5) | 3,202 (18·3) |
| Year of ART initiation, median (IQR) | 2011 (2007–2014) | 2012 (2009–2014) |
| ART regimen, n (%) | ||
| NNRTI + two NRTIs | 10,584 (80·2) | 16,402 (93·8) |
| PI + two NRTIs | 2,096 (15·9) | 969 (5·5) |
| Other | 517 (3·9) | 120 (0·7) |
| CD4 cell count (cells per μL) at ART initiationb, n (%) | ||
| <200 | 6,071 (46·0) | 6,276 (35·9) |
| ≥200 | 6,033 (45·7) | 7,126 (40·7) |
| Missing | 1,045 (7·9) | 4,089 (23·4) |
| Log10 HIV RNA (copies per mL) at ART initiationc, median (IQR) | 4.9 (4·3–5·4) | 4.2 (3·7–4·9) |
| History of tuberculosisd, n (%) | 1,429 (10·8) | 2,141 (12·2) |
| Died during study period, n (%) | 1,167 (8·8) | 1,470 (8·4) |
| Lost to follow-up during study periode, n (%) | 3,174 (24·1) | 7,154 (40·9) |
All others sites include from CCASAnet sites in Argentina, Brazil, Chile, Honduras, and Peru.
CD4 cell count closest within 6 months before or after ART initiation date
HIV RNA value closest within 6 months before or 30 days after ART initiation date
Diagnosis of active pulmonary or extra-pulmonary tuberculosis any time before or within 7 days of ART
Lost to follow-up defined as no clinic contact within 12 months of database closure and not known to have died.
Abbreviations used:
ART: antiretroviral therapy
IQR: interquartile range
NNRTI: non-nucleoside reverse transcriptase inhibitor
NRTI: nucleoside reverse transcriptase inhibitor
PI: protease inhibitor