Fig 2. Setup of the newly developed rTMS system.

(A) Schematic diagram of the present system for achieving constant and effective stimulation targeting the MI of an awake monkey. (B) A thermoplastic mask shaped to fit the monkey’s head is utilized to fix the monkey’s head, secure a sufficient space for a figure-of-eight coil, and contact the coil close to the scalp. (C) The thermoplastic mask is firmly screwed to the upper part of a monkey chair for restraining any head movement. (D) Three laser distance meters are positioned to measure accurate three-dimensional coordinates of the figure-of-eight coil. For details, see “Development of rTMS system” of the Results section.