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. 2021 May 20;17(5):e1009598. doi: 10.1371/journal.ppat.1009598

Fig 5. RGCC controls TIGK proliferation and migration in response to P. gingivalis and is regulated in different cell types.

Fig 5

TIGK cells were transiently transfected with siRNA to RGCC (siRGCC) or scrambled siRNA (siCon) and challenged with P. gingivalis (Pg) or left uninfected (NI). A) Absorbance at 450 nm measured over the times indicated in a BrdU proliferation ELISA. B) Quantitative analysis of TIGK migration through matrigel-coated transwells. C-F) Cells as indicated were challenged with P. gingivalis WT, Δltp1, or Δphp1. Expression of RGCC mRNA was measured by qRT-PCR. Data are expressed relative to noninfected (NI) controls. ** p< 0.01, *** p < 0.005, **** p < 0.001.