Table 1. Characteristics of study participants at enrollment.
| Atopic Dermatitis N = 11 | Control Subjects N = 11 | p-value | ||
|---|---|---|---|---|
| Age (years)1 | 20.6 [16.2–26.2] | 28.8 [22.6–36.8] | 0.15 | |
| Gender2 | Male | 36% | 45% | 1.00 |
| Female | 64% | 55% | ||
| Ethnicity2 | Caucasian | 46% | 36% | 1.00 |
| African American | 18% | 0% | ||
| Asian | 36% | 46% | ||
| Other | 0% | 18% | ||
| Birth history2 | Vaginal delivery | 73% | 91% | 0.59 |
| Caesarian delivery | 27% | 9% | ||
| Medical history2 | Allergies3 | 100% | 36% | 0.0039 |
| Family history2 | Allergies3 | 100% | 64% | 0.09 |
| SCORAD1 | 33 [23.8–45.4] | 0 [0–0] | N/A | |
| AD severity4 | Mild | 36% | N/A | <0.01 |
| Moderate | 46% | |||
| Severe | 18% | |||
| AD medications2 | Emollients | 100% | 0% | <0.01 |
| Topical steroids | 91% | 0% | ||
| Systemics | 18% | 0% | ||
| Skin barrier1 | TEWL | 11.1 [8.6–14.3] | 7.1 [6.0–8.4] | 0.0064 |
| pH | 4.88 [4.67–5.1] | 4.86 [4.6–5.13] | 1.00 | |
| Presence of dermatitis2 | ACV-treated forearm | 73% | 0% | <0.01 |
| Water-treated forearm | 73% | 0% |
1 Geometric mean [95% confidence interval]
2 Percentage of subjects (prevalence)
3 Positive history of allergies included asthma, food, or environmental allergies
4 AD severity was mild (if SCORAD <25), moderate (if SCORAD 25–50), or severe (if SCORAD >50).