Table I.

Severity classification in Graves’ Orbitopathy, recommendations and levels of evidence (from EUGOGO ¹⁰).

Classification	Recommendation	Level of evidence
Sight-threatening GO: DON and/or corneal breakdown	Immediate intervention	IV, C
Moderate-to-severe GO: eye disease with sufficient impact on daily life (lid retraction ≥ 2 mm, exophthalmos ≥ 3 mm, moderate or severe soft tissue involvement)	Active: immunosuppression Inactive: surgical intervention	IV, C
Mild GO: minor impact on daily life (minor lid retraction< 2 mm, exophthalmos < 3 mm, mild soft tissue involvement, transient or no diplopia, corneal exposure responsive to lubricants)	Local measures to alleviate symptoms	IV, C

DON: Dysthyroid Optic Neuropathy; GO: Graves’ Orbitopathy.