Figure 1.

The identification of EXs around MSCs and the expression level of miR-145-5p were detected in MSC-EXs

(a) After MSCs were successfully isolated and cultured, the formation of EXs was analyzed by transmission electron microscopy and nanometer scale. (b) EXs were identified by Western blotting to detect the expression of CD63 and CD9. (c) MiR-145-5p NC and miR-145-5p mimic were transfected into MSCs separately, and qRT-PCR was used to detect the expression level of miR-145-5p in MSC-EXs of each group (n = 3, ***P < 0.001, vs. EX-miR-NC)