Skip to main content
. 2021 Jun 1;59(1):651–659. doi: 10.1080/13880209.2021.1928239

Table 3.

Stability data of seven compounds and IS in rat plasma under various storage conditions (n = 3).

Compounds Spiked concentration (ng/mL) Ambient temperature stability
Long-term stability
Three freeze/thaw cycles
Post-preparative stability
Accuracy (RE%) Precision (RSD%) Accuracy (RE%) Precision (RSD%) Accuracy (RE%) Precision (RSD%) Accuracy (RE%) Precision (RSD%)
Rg1 2.39 −5.07 6.9 3.52 9.6 −0.13 6.50 5.72 10.5
  95.6 2.86 2.07 −2.33 5.5 2.26 1.38 5.9 4.4
Re 1.20 −0.83 14.6 7.21 15.0. −6.71 3.0 6.2 12.1
  47.9 −0.53 5.40 5.83 8.00 1.33 5. 5 5.44 3.6
NGR1 2.39 −4.35 3.4 2.05 5.93 −7.43 11.1 4.64 5.1
  95.6 −0.77 3.13 −9.83 9.24 6.54 6.43 2.3 3.4
Rd 9.56 5.26 8.6 6.45 10.7 −3.96 10.9 −4.23 13.8
  191.3 2.75 7.7 1.30 0.74 7.37 5.25 2.51 4.03
Rb1 7.65 −1.63 6.94 −4.70 11.23 0.54 5.81 1.85 3.45
  1530.2 −4.93 8.28 4.35 10.94 −3.46 7.14 −1.42 5.52
Rg5 19.1 2.92 6.42 7.46 8.12 4.62 9.53 10.6 3.36
  191.3 3.48 6.24 6.28 5.99 5.23 10.2 0.25 1.29
Rk1 19.1 5.03 5.18 3.25 8.36 7.25 8.66 3.09 8.43
  191.3 1.35 3.95 7.38 1.52 0.95 8.33 5.15 2.86
IS 2.39 6.78 1.18 −9.62 2.17 1.99 2.02 −8.93 6.58