Figure 6.
Duration of antibody response of Sad23L-nCoV-S and Ad49L-nCoV-S vaccines in mice and Rhesus macaques. (A) RBD-BAb and (B) pNAb were measured for 29 weeks in a single dose of Sad23L-nCoV-S (Prime 1) or Ad49L-nCoV-S (Prime 2), or prime-boost (Sad23L-nCoV-S and Ad49L-nCoV-S) vaccinated C57BL/6 and BALB/c mice. (C) RBD-BAb and (D) pNAb were measured for 29 weeks in prime-boost (Sad23L-nCoV-S/Ad49L-nCoV-S) vaccinated or sham (Sad23L-GFP/Ad49L-GFP) rhesus macaques. Mean Ab titers are presented in each group.