TABLE II.
Bare-metal stents coated with electrospun nanofibers tested in vivo.
| Type of coating | Description | Active agent | Animal model | Results | References |
|---|---|---|---|---|---|
| Electrospun nanofibrous coatings | PCL and human serum albumin | Paclitaxel | In vivo rabbit iliac artery | Induced weaker neointimal growth over 6 months | 197 |
| PLGA nanofibers on BMS | Propylthiouracil | In vivo rabbit injured aorta | Reduced neointimal hyperplasia and enhanced re-endothelialization | 199 | |
| PLGA nanofibers on BMS | Ticagrelor | In vivo rabbit abdominal aorta | Minimal neointimal formation and favored endothelial recovery | 203 | |
| PLGA nanofibers on SS stents | Acetylsalicylic acid | In vivo rabbit denuded artery | Promoted re-endothelialization | 204 | |
| PLGA nanofibers on BMS | Vildagliptin | In vivo rabbit abdominal aorta | Accelerated endothelial recovery and decreased SMC hyperplasia | 205 | |
| poly-L-lactic acid (PLLA) cable tie type stents | Rapamycin | In vivo rabbit denuded artery | Reduced neointimal hyperplasia | 206 |