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. 2021 Jun 3;108:274–281. doi: 10.1016/j.ijid.2021.05.069

Table 1.

Clinical causes of death and documented comorbidities as reported in the death certificates of six young decedents with COVID-19.

Case Age Gender Symptoms to death Immediate COD Condition leading to COD Underlying cause Comorbidities/conditions
1 26 years Male 181 days Mesenteric ischemia SARS-CoV-2 pneumonia Coinfection with CMV/HHV-1
SSC
History of pulmonary thromboembolism
OSA
Gastritis
Nicotine abuse
2 28 years Female 16 days Acute liver failure Celiac trunk ischemia COVID-19 with ARDS Coinfection with CandidaR
ight heart insufficiency
Asthma
Obesity (WHO grade III)
3 30 years Female 18 days Septic MOF Sepsis Intestinal GvHD COVID-19
Coinfection with CMV
Toxoplasmosis
Dermal GvHD
t-MDS (allo-HSCT, ruxolitinib)
Ewing sarcoma (chemotherapy)
Graves’ disease
4 33 years Male 30 days Hemorrhagic shock Airway bleeding COVID-19 Acute pulmonary thromboembolism
5 45 years Female 19 days Septic MOF SARS-CoV-2 pneumonia Viral pneumonia Staph. aureus coinfection
Mesenterial infarction
Arterial hypertension
Asthma
COPD
6 46 years Male 18 days Cardiogenic shock SARS-CoV-2 pneumonia Dilated cardiomyopathy Chronic left ventricular heart thrombus
Anxiety disorder
Benzodiazepine abuse

Abbreviations: cause of death (COD), multiple organ failure (MOF), severe acute respiratory syndrome coronavirus type 2 (SARS CoV-2), coronavirus disease 2019 (COVID-19), cytomegalovirus (CMV), human herpes virus 1 (HHV-1), secondary sclerosing cholangitis (SCC), obstructive sleep apnea (OSA), World Health Organization (WHO), graft-versus-host disease (GvHD), therapy-induced myelodysplastic syndrome (t-MDS), allogeneic hematopoietic stem cell transplantation (allo-HSCT), Staphylococcus (Staph.), chronic obstructive pulmonary disease (COPD).