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. 2021 May 5;594(7861):77–81. doi: 10.1038/s41586-021-03519-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 4 — a, Pan-specific duplication of the CLN3 locus and bonobo-specific deletion of IGFL1. HiFi read depth and whole-genome shotgun detection of bonobo, chimpanzee, orangutan, gorilla and human individuals relative to GRCh38 detect these events (top), which are validated by interphase FISH of each species using fosmid clones spanning the region (bottom). b, Pan-specific duplication of the EIF3C locus and bonobo-specific deletion of SAMD9. HiFi read depth and whole-genome shotgun detection of bonobo, chimpanzee, orangutan, gorilla and human individuals relative to GRCh38 detect these events (top), which are validated by interphase FISH of each species using fosmid clones spanning the region (bottom). Genomes were included from the following individuals (from top to bottom): bonobo (Pan_paniscus_A915_Kosana, A927_Salonga, A922_Catherine, A917_Dzeeta, A918_Hermien, A924_Chipita, A926_Natalie, A928_Kumbuka, A914_Hortense, A919_Desmond, A925_Bono); chimpanzee (Pan_troglodytes_troglodytes_A958_Doris, A957_Vaillant, A960_Clara, Pan_troglodytes_verus_Clint); orangutan (Pongo_abelii_A950_Babu, Pongo_pygmaeus_A944_Napoleon); gorilla (Gorilla_gorilla_gorilla_KB4986_Katie); human (AFR_Aari_ETAR005_F, AMR_Nahua_Mex20_M, EA_Mongola_HGDP01228_M, SA_Kalash_HGDP00328_M, WEA_FinlandFIN_HG00360_M).