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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Clin Nutr. 2021 Jan 23;40(5):3032–3036. doi: 10.1016/j.clnu.2021.01.020

Table 1.

Fasting levels (before and after 5 days of treatment) and postprandial AUCs (after smoothie consumption on day 5) of BCAA, ketone bodies, glucose and citrate with walnut vs placebo treatment.

Placebo Walnut p
Day 1 Day 5 Day 1 Day 5
Fasting measurements
Amino Acid Concentrations
Branched-Chain Amino Acids (BCAA) (μmol/L) 375.00 ± 19.85 390.3 ± 22.42 379.9 ± 23.61 374.9 ± 29.23 .180
Valine (μmol/L) 221.00 ± 10.64 228.00 ± 12.19 217.00 ± 11.65 213.60 ± 14.82 .047
Leucine (μmol/L) 118.44 ± 10.35 117.30 ± 6.30 113.00 ± 10.00 115.60 ± 12.52 .651
Isoleucine (μmol/L) 38.63 ± 6.02 49.56 ± 6.12 53.89 ± 4.20 45.90 ± 6.69 .001
Alanine (μmol/L) 310.56 ± 18.79 382.10 ± 23.26 333.90 ± 30.95 388.20 ± 25.39 .931
Ketone Bodies
Ketone Body Concentrations (μmol/L) 179 ± 28.73 106.61 ± 29.96 114.94 ± 13.19 114.71 ± 16.80 .160
Beta-hydroxy-butyrate (μmol/L) 119.88 ± 23.63 73.42 ± 21.99 69.01 ± 8.01 80.62 ± 12.90 .023
Aceto-acetate (μmol/L) 20.93 ± 5.00 8.44 ± 2.24 16.83 ± 3.73 10.32 ± 4.50 .928
Acetone (μmol/L) 38.19 ± 4.61 24.75 ± 8.38 29.11 ± 6.96 23.79 ± 3.87 .772
Small Molecule Metabolites
Glucose (mg/dL) 95.34 ± 2.49 91.37 ± 2.69 97.94 ± 2.82 93.08 ± 4.03 .918
Citrate (mg/dL) 100.11 ± 13.93 109.30 ± 7.64 99.50 ± 8.31 113.00 ± 10.77 .863
Smoothie Postprandial AUC measurements
Amino Acid Concentrations
Branched-Chain Amino Acids (BCAA) (μmol/L*min) 52256 ± 2384 57137 ± 3061 .004
Valine (μmol/L*min) 33156 ± 1255 34461 ± 1394 .060
Leucine (μmol/L*min) 14528 ± 1044 17163 ± 1305 .023
Isoleucine (μmol/L*min) 5538 ± 675 5801 ± 854 .350
Alanine (μmol/L*min) 66543 ± 2366 67875 ± 3756 .630
Ketone Bodies
Ketone Body Concentrations (μmol/L*min) 23316 ± 2503 20325 ± 2114 .069
Beta-hydroxy-butyrate (μmol/L*min) 14876 ± 1986 12774 ± 1941 .091
Aceto-acetate (μmol/L*min) 3949 ± 507 3810 ± 344 .790
Acetone (μmol/L*min) 4535 ± 621 4027 ± 449 .150
Small Molecule Metabolites
Glucose (mg/dL*min) 18123.6 ± 476 17740.8 ± 350 .292
Citrate (mg/dL*min) 24198 ± 1851 24606 ± 1665 .737