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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Psychosom Res. 2021 Mar 24;146:110434. doi: 10.1016/j.jpsychores.2021.110434

Table 4.

Biomarkers Included in the Measurement of Allostatic Load

Body System/Bio marker First Author, Year
Allen 2019 Cuevas, 2019 Currie, 2019a Currie, 2019b Daly, 2019 Ong, 2017 Rosemberg, 2019 Thomas, 2019 Upchurch, 2015 Vadiveloo, 2017 Zilioli, 2017
Cardiovascular
Resting heart rate X X X X X
Systolic BP X X X X X X X X X X X
Diastolic BP X X X X X X X X X X
Resting pulse pressure X
Immune/Inflammation
CRP X X X X X X X X X X X
Interleukin-6 X X X X X
Fibrinogen X X X X
sE-selectin X X X
sICAM-1 X X X
WBC count X
Metabolic
HbA1c X X X X X X X X
Glucose X X X X X X X
BMI X X X X X X X X X
Waist circumference X X X X X
Waist-to-hip ratio X X X X X
Insulin resistance X X X
Triglycerides X X X X X X X
HDL cholesterol X X X X X X X X
LDL cholesterol X X X X X
Total cholesterol X X X X
Ratio of total to HDL cholesterol X
Neuroendocrine
Cortisol X X X X X X
CAR X X
DHEA-S X X X X X X
Epinephrine X X X X X X
Norepinephrine X X X X X X
SDRR X X X
RMSSD X X X
High frequency spectral power X X X
Low frequency spectral power X X X

Notes: BP: Blood Pressure, sE-selectin: soluble adhesion molecule E-selectin, sICAM: soluble intracellular adhesion molecule-1, WBC: white blood cell, HbA1c: glycated hemoglobin, BMI: body mass index, HDL: high-density lipoprotein, LDL: low-density lipoprotein, CAR: cortisol awakening response, DHEA-S: dehydroepiandrosterone sulfate, SDRR: standard deviation of R-R (heartbeat to heartbeat) intervals, RMSSD: root mean square of successive differences