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Overview of schema (A) and schedule of study procedures (B) for canine OS patients enrolled in the Standard of Care (SOC) vs. SOC + sirolimus (SOC + S) clinical trials. CXR = 3-view thoracic (chest) radiographic assessment. PBMC = Peripheral Blood Mononuclear Cells. PE = Physical Exam. PD = Progressive Disease. PK = pharmacokinetic assessment of drug levels.
