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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Dev Biol. 2021 Mar 20;476:1–10. doi: 10.1016/j.ydbio.2021.03.011

Figure 2. Hand1 and Hand2 genetically interact in the cardiac NCCs.

Figure 2.

Whole mount preparations (A-E) and hematoxylin and eosin-stained (F-J) E16.5 hearts and aortic arches in which NCC-specific Hand1 and/or Hand2 has been conditionally ablated. Aortic arches are schematized in A-E. Arrowhead, VSD; Asterisk, PTA; Ao, aorta; BCT, brachiocephalic trunk; LA, left atrium; LCC, left common carotid; LSA, left subclavian artery; LV, left ventricle; RA, right atrium; RCC, right common carotid; RSA, right subclavian artery; RV, right ventricle. (F’-J’) higher magnification images of F-J to better show structures.