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OFT defects in HAND factor SHF mutants.
| Genotype | n | membranous VSD |
Phenotypically Normal |
|---|---|---|---|
| Hand1fx/fx; Hand2+/fx; (−) | 3 | 0 (0%) | 3 (100%) |
| Hand1+/fx; Hand2+/fx;SHF-Cre(+) | 8 | 0 (0%) | 8 (100%) |
| Hand1fx/fx;Hand2+/fx;SHF-Cre(+) | 12 | 3 (25%) | 9 (75%) |
VSD, ventricular septal defect.
