Table 3.
Genotypes frequencies and results of comparison with Hardy–Weinberg expectations
| Gene SNP |
Genotype | Patients (n = 209) | Controls (n = 202) | ||||
|---|---|---|---|---|---|---|---|
| Genotypic frequency | Expected frequency | χ2 | Genotypic frequency | Expected frequency | χ2 | ||
| % | % | % | % | ||||
|
LEP rs7799039 2548 G>A |
GG | 33 | 30 | 1,758 | 34 | 33 | 0,167 |
| GA | 43,5 | 50 | 47 | 49 | |||
| AA | 23,5 | 20 | 19 | 18 | |||
|
LEPR rs1137101 223Gln>Arg |
Gln,Gln | 31,5 | 33 | 0,575 | 30 | 29 | 0,199 |
| Gln,Arg | 52,5 | 49 | 47,5 | 50 | |||
| Arg,Arg | 16 | 18 | 22,5 | 21 | |||
|
LEPR rs1137100 109Lys>Arg |
Lys,Lys | 47 | 47,5 | 0,08 | 50,5 | 47,5 | 1,825 |
| Lys,Arg | 44 | 43 | 37 | 43 | |||
| Arg,Arg | 9 | 9,5 | 12,5 | 9,5 | |||
Results statistically significant are those for which the level of significance was less than 0.05