Table 6.

Incidence of LEP and LEPR genes polymorphisms in healthy women and breast cancer patients

Gen SNP	Genotype	Patients		Controls		WW vs. WV, VV	WW, WV vs. VV	W vs. V
		n = 209	%	n = 202	%
LEP rs7799039 2548 G>A	GG	71	34	67	33	p = 0.9153	p = 0.2162	p = 0.3909
	GA	98	47	88	43,5
	AA	40	19	47	23,5
LEPR rs1137101 223Gln>Arg	Gln,Gln	66	31,5	61	30	p = 0.8280	p = 0.0500	p = 0.2233
	Gln,Arg	110	52,5	96	47,5
	Arg,Arg	33	16	45	22,5
LEPR rs1137100 109Lys>Arg	Lys,Lys	98	47	102	50.5	p = 0.6168	p = 0.0935	p = 0.6997
	Lys,Arg	92	44	75	37
	Arg,Arg	19	9	25	12,5

Bold values denote statistical significance at the p < 0.05 level

WW wild type homozygous, WV heterozygous, VV polymorphic homozygous