Table 2.
Results of multivariate linear regression analysis* examining factors associated with breast epigenetic age acceleration.
| Grim age | Pan-tissue age | Hannum age | Phenotypic age | Skin and Blood age | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β | p | β | p | β | p | β | p | β | p | |
| Age | 0.64 | <0.0001 | 0.66 | <0.0001 | 0.33 | <0.0001 | 0.20 | 0.0041 | 0.58 | <0.0001 |
| Body mass index | ||||||||||
| Overweight | 1.27 | 0.012 | 0.81 | 0.24 | 1.62 | 0.046 | 4.25 | 0.035 | 2.81 | 0.066 |
| Obese | 1.69 | 0.00065 | 0.91 | 0.17 | 2.4 | 0.0025 | 5.21 | 0.0082 | 3.74 | 0.012 |
| Age at menarche | −0.24 | 0.064 | −0.23 | 0.20 | 0.024 | 0.90 | −0.36 | 0.48 | −0.72 | 0.063 |
models adjusted for chronologic age, BMI, and age at menarche.