TABLE 3.
Gene | Published skipped exon | Published gene silenced | Our result | Transcript | Ratio proportion PCBP2/NT | −log(adj p) |
RUNX1 | 6 | PCBP2# | Skipped exon 6 | ENST00000399240.5 | 1.55 | 1.9 |
CDK2 | 5 | PCBP1/2$ | Skipped exon 5 | ENST00000354056.4 | 1.62 | 3.6 |
SH2B1 | 9 | PCBP1/2 | No exon 9 exclusion | |||
TARS2 | 14 | PCBP1/2; PCBP2 (n.s.) | No exon 14 exclusion | |||
CTTN | 11 | PCBP1/2; PCBP2 | Skipped exon 11 | ENST00000376561.7 | 1.51 | 5.9 |
VKORC1 | 2 | PCBP1/2 | No exon 2 exclusion | |||
TRPT1 | 7 | PCBP1/2 | No exon 7 exclusion | |||
TFR2 | 2 | PCBP1/2 | Not expressed | |||
AP1G2 | 3 | PCBP1/2 | No exon 3 exclusion | |||
WNK4 | 8 | PCBP1/2 | Skipped exon 8 | ENST00000587705.5 | 4.42 | 1.7 |
ARHGAP4 | 9 | PCBP1/2 | Not expressed | |||
STAT2 | 18 | PCBP1/2 | No exon 18 exclusion |
#Depletion of PCBP2 only; $Co-depletion of PCBP1 and PCBP2; n.s., not significant.