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. 2021 May 20;9:674705. doi: 10.3389/fchem.2021.674705

Figure 4.

Figure 4

Synthetic strategies of triazolyl containing cyclopeptidomimetics. (A) CuAAC in solution-phase peptide synthesis; (B) incorporation of triazole during SPPS; (C) attachment of triazole to the solid support by CuAAC; (D) conjugation of peptide fragment after CuAAC in solution (Valverde and Mindt, 2012).