Table 1.

Synthetic techniques to obtain molecular structures containing triazolyl moieties reported in this review.

	Method of synthesis	Yield [%]	References
Metal catalysed reaction	CuAAC RuAAC AgAAC Zinc-catalysed azide-alkyne cycloaddition Copper-catalysed cascade reaction Transition metal catalysed reaction Ultrasound copper-catalysed reaction with no ligands	– – 68–99 49–76 64–68 52–85 ≈80	Huisgen, 1963 Zhang et al., 2005 McNulty and Keskar, 2012 Smith and Greaney, 2013 Sudheendran et al., 2014 Ueda and Nagasawa, 2009 Cintas et al., 2010
SPPS	Pseudo-dipeptide containing building blocks	–	Valverde et al., 2012
Microwave-assisted reaction	Copper-mediated one-pot three-component synthesis Side chain-to-side chain cyclisation	12–55 25.5	Xu et al., 2015 D'Ercole et al., 2020
Others	1,5-electrocyclisation of β-substituted α-diazocarbonyl compounds Non-reductive conditions Metal free azide-alkyne cycloaddition	47–93 76–99 37–92	Jordão et al., 2011 Kuang et al., 2010 Kwok et al., 2010