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. 2021 May 20;8:668653. doi: 10.3389/fcvm.2021.668653

Table 1.

General characteristics of study groups divided according to cardiac rhythm.

Total Subgroup
Sinus rhythm Atrial fibrillation p
All patients, N (%) 113 (100) 90 (79.65) 23 (20.35)
Males, N (%) 65 (57.52%) 50 (55.56) 15 (65.22) 0.403
Age (years) 64.000 (58.0–69.0) 64.0 (55.00–68.00) 66.0 (62.00–73.00) 0.039
Body surface area (BSA) (m2) 1.949 (1.782–2.132) 1.935 (1.71–2.11) 2.049 (1.88–2.33) 0.034
SBP (mmHg) 134.0 (120.0–146.0) 135 (120–147) 130 (124–135) 0.138
DBP (mmHg) 80.0 (70.0–86.0) 80 (70–86) 83 (70–88) 0.276
Heart rate on admission (bpm) 70.0 (65.0–80.0) 70 (64–77) 80 (67–90) 0.004
Width of the QRS complex (ms) 99 (84–121.5) 98 (84–116) 112 (96–136) 0.004
QTcBAz (ms) 442 (425–475) 437 (424–462) 467.5 (437–494.5) 0.005
Ischemic etiology, N (%) 48 (42.48%) 43 (47.78) 5 (21.74) 0.024
Non-ischemic etiology, N (%) 65 (57.52%) 47 (52.22) 18 (78.26) 0.024
NYHA class on admission 2 (2.0–2.5) 2 (2.0–2.0) 3 (2.5–3.0) <0.001
6MWT distance (m) 370.5 (290.7–449.2) 378.4 (306.1–457.0) 292.35 (201.3–349.3) 0.001
KCCQ score (point) 70.05 (50.0–83.33) 73.96 (57.29–83.98) 52.60 (38.28–71.15) 0.002
Coronary artery disease, N (%) 53 (46.90) 47 (52.2) 6 (26.09) 0.025
Mitral regurgitation, N (%) 55 (48.67%) 39 (43.33) 16 (69.57) 0.025
Aortic regurgitation, N (%) 16 (14.16%) 11 (12.22) 5 (21.74) 0.243
Tricuspid regurgitation, N (%) 40 (35.40%) 25 (27.78) 15 (65.22) 0.001
Aortic stenosis, N (%) 5 (4.42%) 3 (3.33) 2 (8.69) 0.268
Diabetes mellitus, N (%) 31 (27.43) 22 (24.44) 9 (39.13) 0.159
Arterial hypertension, N (%) 83 (73.45) 61 (67.78) 22 (95.65) 0.007
Hyperlipidemia, N (%) 86 (76.11%) 69 (76.67) 17 (73.91) 0.782
ACEI, N (%) 75 (66.37) 60 (66.67) 15 (65.22) 0.896
ARB, N (%) 18 (15.93) 13 (14.44) 5 (21.74) 0.522
BB, N (%) 98 (86.73) 78 (86.67) 20 (86.96) 1.00
MRA, N (%) 52 (46.02) 39 (43.33) 13 (56.52) 0.257
Diuretics, N (%) 65 (57.52) 47 (52.22) 18 (78.26) 0.033

Data are given as median (interquartile range) unless otherwise indicated. A p-value of <0.05 is considered statistically significant.

DBP, diastolic blood pressure; SBP, systolic blood pressure; QTcBAz, QT interval corrected for heart rate; NYHA, New York Heart Association; 6MWT, 6-min walk test; KCCQ, Kansas City Cardiomyopathy Questionnaire; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blockers; BB, beta blockers; MRA, mineralocorticoid receptor antagonists. Bold values are statistically significant data.