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. 2021 May 26;6(6):e396–e407. doi: 10.1016/S2468-2667(21)00066-9

Table 1.

Associations between neighbourhood characteristics and new-onset diseases and health conditions*

n/N HR (95% CI)
Education (high vs low) Income (high vs low) Unemployment (low vs high) Green space (high vs low)
Death 3438/114 786 0·86 (0·80–0·92) 0·72 (0·67–0·77) 0·84 (0·78–0·90) 0·87 (0·81–0·93)
Infections 3032/112 644 0·97 (0·90–1·05) 0·92 (0·85–0·99) 0·96 (0·89–1·03) 0·93 (0·86–1·00)
Cancer 5502/112 666 1·02 (0·96–1·08) 1·03 (0·98–1·09) 1·01 (0·96–1·07) 1·06 (1·00–1·11)
Diseases of the blood 618/114 382 0·95 (0·80–1·12) 0·76 (0·64–0·90) 0·96 (0·81–1·13) 0·96 (0·82–1·12)
Endocrine diseases 6885/113 086 0·82 (0·78–0·86) 0·83 (0·79–0·88) 0·85 (0·81–0·90) 0·92 (0·87–0·96)
Diabetes 5611/112 785 0·80 (0·76–0·85) 0·81 (0·77–0·86) 0·84 (0·80–0·89) 0·91 (0·87–0·96)
Obesity (requiring hospital treatment) 415/114 786 0·61 (0·50–0·76) 0·73 (0·59–0·89) 0·69 (0·56–0·85) 0·94 (0·78–1·14)
Mental and behavioural disorders 1941/112 942 0·85 (0·77–0·93) 0·73 (0·66–0·80) 0·82 (0·75–0·90) 0·82 (0·75–0·90)
Disorders due to substance abuse 696/114 786 0·64 (0·54–0·75) 0·61 (0·52–0·72) 0·70 (0·59–0·82) 0·85 (0·73–0·99)
Psychotic disorders 720/113 800 0·88 (0·75–1·03) 0·63 (0·54–0·74) 0·83 (0·71–0·97) 0·70 (0·60–0·81)
Mood disorders 951/113 892 0·94 (0·82–1·08) 0·75 (0·66–0·86) 0·85 (0·74–0·97) 0·79 (0·69–0·90)
Diseases of the nervous system 5426/110 948 0·93 (0·87–0·98) 0·96 (0·90–1·01) 0·86 (0·81–0·91) 1·03 (0·97–1·08)
Sleep disorders 2846/114 786 0·82 (0·76–0·89) 0·84 (0·78–0·91) 0·81 (0·75–0·87) 1·07 (0·99–1·15)
Diseases of the eye 5472/113 149 0·99 (0·94–1·05) 0·94 (0·89–1·00) 0·98 (0·92–1·03) 0·96 (0·91–1·01)
Diseases of the ear 930/113 829 0·93 (0·81–1·07) 0·92 (0·81–1·06) 0·83 (0·72–0·95) 1·02 (0·89–1·16)
Diseases of the circulatory system 8410/107 313 0·94 (0·90–0·98) 0·95 (0·90–0·99) 0·89 (0·85–0·93) 1·03 (0·99–1·08)
Hypertension 5008/106 221 0·95 (0·90–1·01) 0·98 (0·92–1·03) 0·89 (0·84–0·95) 1·02 (0·96–1·07)
Ischaemic heart diseases 2558/113 585 0·95 (0·88–1·03) 0·95 (0·87–1·03) 0·81 (0·74–0·88) 1·02 (0·95–1·11)
Angina pectoris 1036/113 988 0·97 (0·85–1·10) 1·08 (0·94–1·23) 0·88 (0·77–1·00) 1·27 (1·12–1·43)
Heart failure 539/114 604 0·84 (0·70–1·00) 0·69 (0·57–0·82) 0·72 (0·60–0·87) 1·00 (0·84–1·18)
Cerebrovascular diseases 1382/114 346 1·00 (0·89–1·12) 0·77 (0·69–0·86) 0·85 (0·76–0·96) 0·94 (0·84–1·04)
Stroke 1155/114 449 0·98 (0·87–1·11) 0·75 (0·66–0·84) 0·82 (0·73–0·93) 0·91 (0·81–1·02)
Intracerebral haemorrhage 191/114 738 0·78 (0·58–1·06) 0·54 (0·40–0·73) 0·72 (0·53–0·96) 0·68 (0·51–0·91)
Diseases of the respiratory system 5882/106 991 0·89 (0·85–0·94) 0·85 (0·81–0·90) 0·90 (0·85–0·95) 0·96 (0·91–1·01)
Chronic obstructive bronchitis 491/114 681 0·80 (0·66–0·97) 0·55 (0·45–0·67) 0·67 (0·56–0·82) 0·77 (0·64–0·92)
Diseases of the digestive system 9909/106 081 0·89 (0·85–0·93) 0·97 (0·93–1·01) 0·90 (0·86–0·94) 1·03 (0·99–1·08)
Diseases of the skin 1008/113 627 0·87 (0·76–0·99) 0·81 (0·71–0·92) 0·73 (0·64–0·83) 0·99 (0·88–1·13)
Diseases of the musculoskeletal system 13 435/100 749 0·90 (0·86–0·93) 1·02 (0·98–1·06) 0·94 (0·91–0·98) 1·11 (1·07–1·14)
Osteoarthritis 5964/114 786 0·81 (0·77–0·85) 0·97 (0·92–1·02) 0·87 (0·82–0·91) 1·09 (1·04–1·15)
Soft tissue disorders 5128/114 786 0·87 (0·82–0·92) 1·05 (0·99–1·12) 0·92 (0·87–0·97) 1·18 (1·11–1·24)
Diseases of the genitourinary system 9517/103 653 0·95 (0·91–0·99) 1·04 (1·00–1·09) 0·96 (0·92–1·01) 1·10 (1·06–1·15)
Pregnancy complications (hypertension) 377/87 012 1·19 (0·96–1·48) 1·22 (0·98–1·53) 1·47 (1·19–1·83) 1·02 (0·83–1·25)
Digestive and abdominal symptoms 2160/114 786 0·84 (0·76–0·92) 0·89 (0·81–0·97) 0·82 (0·75–0·90) 1·13 (1·04–1·23)
Poisoning 453/114 786 0·73 (0·59–0·89) 0·61 (0·50–0·75) 0·63 (0·52–0·78) 0·76 (0·63–0·91)
Self-harm 369/91 131 0·78 (0·63–0·97) 0·65 (0·52–0·80) 0·71 (0·58–0·89) 0·67 (0·54–0·83)

HR=hazard ratio. ICD-10=International Classification of Diseases, Tenth Revision. Detailed results for all 79 health outcomes are provided in appendix 1 (pp 15–18).

*

All disease groups (ICD-10 chapters) are presented, but only specific health conditions that were associated with any of the neighbourhood characteristics after Bonferroni correction are shown.

Adjusted for age, sex, education, and cohort.