Table 2.
Summary of differential metabolites to distinguish ACS patients from controls.
| Metabolites | M/Z | RT (min) | Type | VIP value | Fold change | p-value |
|---|---|---|---|---|---|---|
| Acetoin | 89.060 | 2.35 | [M + H]+ | 2.73485 | 0.767718 | 0.000157 |
| D-fructofuranose | 179.056 | 2.99 | [M – H]– | 2.43371 | 1.460485 | 1.25E-06 |
| LPE(16:0p) | 438.296 | 13.54 | [M + H]+ | 2.06323 | 1.424668 | 8.29E-06 |
| Diphenylsulfoxide | 203.052 | 1.45 | [M + H]+ | 1.99240 | 1.374833 | 0.00012 |
| 5-oxo-D-proline | 129.127 | 3.24 | [M]+ | 1.95935 | 1.221804 | 0.000382 |
| 3-hydroxy-3-methylglutaric acid | 163.039 | 0.43 | [M + H]+ | 1.94675 | 1.170112 | 0.00101 |
| Adenosine | 265.949 | 9.19 | [M – H]– | 1.83565 | 0.873886 | 0.004219 |
| L-cystine | 239.127 | 11.68 | [M – H]– | 1.82551 | 0.875852 | 0.002183 |
| creatinine | 114.066 | 1.14 | [M + H]+ | 1.78853 | 1.171524 | 0.001768 |
| Phosphatidylethanolamine lyso 20:4 | 500.277 | 12.67 | [M – H]– | 1.67118 | 1.259715 | 0.001234 |
| N-butylbenzenesulfonamide | 214.089 | 10.25 | [M + H]+ | 1.65585 | 0.938917 | 0.00273 |
| 3-methyl-2-oxovaleric acid | 129.056 | 4.93 | [M – H]– | 1.57132 | 1.174449 | 0.003611 |
| o-toluic acid | 137.059 | 0.43 | [M + H]+ | 1.54001 | 1.123012 | 0.003452 |
| 8,11-eicosadiynoic acid | 303.231 | 14.86 | [M – H]– | 1.53945 | 1.303894 | 0.003295 |
| LPE(18:2) | 478.291 | 12.75 | [M + H]+ | 1.53936 | 0.823716 | 0.015186 |
| L-phenylalanine | 164.071 | 3.54 | [M – H]– | 1.48969 | 1.120638 | 0.003564 |
| O-acetyl-L-Carnitine | 238.931 | 10.43 | [M – H]– | 1.40231 | 1.148321 | 0.009212 |
| 2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid | 239.092 | 9.35 | [M – H]– | 1.36899 | 0.779988 | 0.024651 |
| PC(14:0/0:0) | 468.306 | 12.16 | [M + H]+ | 1.36663 | 0.850007 | 0.032162 |
| Acetoacetate | 107.967 | 9.71 | [M]+ | 1.3192 | 0.897832 | 0.03983 |
| 5-Isopropylbicyclo[3.1.0]hexan-2-one | 139.111 | 0.09 | [M + H]+ | 1.30839 | 1.119695 | 0.020492 |
| Galactitol | 180.973 | 4.61 | [M – H]– | 1.26313 | 0.8763 | 0.037811 |
| Indoxylsulfuric acid | 212.001 | 5.26 | [M – H]– | 1.24185 | 1.287774 | 0.025296 |
| Phosphatidylethanolamine lyso 16:0 | 452.278 | 13.14 | [M – H]– | 1.21647 | 0.86635 | 0.041439 |
| Choline | 104.107 | 1.11 | [M + H]+ | 1.13647 | 1.081594 | 0.045266 |
| LPI(18:2) | 595.288 | 12.64 | [M – H]– | 1.11604 | 1.169562 | 0.041938 |
| Valine | 118.086 | 8.92 | [M + H]+ | 1.06623 | 1.138983 | 0.038275 |
| LPC(20:4) | 544.337 | 12.74 | [M + H]+ | 1.01176 | 1.125107 | 0.042242 |
M/Z, mass to charge ratio; RT, retention time; VIP, variable importance in the projection.