Table 3.
Diagnostic rating sheet for Probable PDD recommended by the MDS Task Force.
| LSPD (N = 85) | MDS PDD Level I | MDS PDD Level II |
|---|---|---|
| Yes (%) | Yes (%) | |
| 1.Parkinson's disease | 100 | 100 |
| 2.Parkinson's disease developed before dementia | 100 | 100 |
| 3.MMSE** <22 (0–2 yrs education); <24 (3–6 yrs education); <27 (≥7 yrs education) | 69.4 | 69.4 |
| 4.Dementia has impact on ADLs | 87.1 | 87.1 |
| 5.Impaired cognition (for yes, at least of 2 of 4 cognitive domains below are abnormal) | 79.1 | 67.9 |
| 5 a) Attention | 48.2 | * |
| 5 b) Executive Function | 87.1 | 56.5 |
| B1) Working memory | * | 25.9 |
| B2) Conceptualization | * | 11.8 |
| B3) Set activation | * | 68.7 |
| B4) Set shifting | * | 85.9 |
| B5) Set maintenance | * | 55.2 |
| B6) Behavioral control | * | 30.1 |
| 5 c) Instrumental Functions | * | 55.6 |
| C1) Language | * | 11.1 |
| C2) Visuo-Constructive | 65.5 | 60.8 |
| C3) Visuo-Spatial | * | 67.1 |
| C4) Visuo-Perceptive | * | 61.1 |
| 5 d) Memory | 62.4 | 68.7 |
| D1) Only medial temporal/hippocampal component | * | 18.1 |
| D2) Only subcortico-frontal component | * | 15.7 |
| D3) Both components | * | 44.6 |
| 6.Absence of major depression | 18.6 | * |
| 7.Absence of delirium | 98.8 | * |
| 8.Absence of other abnormalities that obscure diagnosis | 89.4 | 89.4 |
| Behavioral symptoms (one of delusions, hallucinations, depression, excessive daytime sleepiness) | 74.7 | 74.7 |
| Probable PDD (items 1–8 must all be YES) | 6.2 | 55.9*** |
| Probable PDD Inconclusive | 23.5 | 1.2 |
| Possible PDD | 0 | 8.3 |
| Total Score (0/8) Mean (SD) | 6.3 (1.0) | * |
MDS PDD, Parkinson's Disease dementia criteria recommended by Movement Disorder Society Task Force (11); PDD, Parkinson's Disease dementia; MMSE, Mini-Mental State Exam; ADLs, Activities of daily living.
*
Not applicable in this Level.
**
We considered education-adjusted MMSE cutoff scores (Portuguese population).
***
Items 6 and 7 not applicable for MDS PDD Level II.