Table 5.

Classification of LSPD by different diagnostic criteria using MDS PDD Level II criteria as the gold-standard.

Classification	MDS PDD Level I	DSM-IV	DSM-5 MMSE adjusted for education	DSM-5 MMSE adjusted for age and education	DSM-5 MMSE adjusted for dementia	DSM-5 NPA
True positive	3	45	52	54	49	54
False positive	0	5	0	3	2	5
True negative	30	25	30	27	28	23
False negative	31	9	2	0	5	0
PPV (%)	100	90.0	100	94.7	96.1	91.5
NPV (%)	49.2	73.5	93.8	100	84.8	100
Sensitivity (%)	8.8	83.3	96.3	100	90.7	100
Specificity (%)	100	83.3	100	90.0	93.3	82.1
Kappa coefficient*	0.1	0.6	0.9	0.9	0.8	0.9

LSPD, Late-stage Parkinson's Disease patients; MDS PDD, Parkinson's Disease dementia criteria recommended by Movement Disorder Society Task Force (11); DSM-IV, Parkinson's Disease dementia criteria recommended by Diagnostic and Statistical Manual of Mental Disorders – Fourth Edition (15); DSM-5, Parkinson's Disease dementia criteria recommended by Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (16); MMSE, Mini-Mental State Exam; NPA, Neuropsychological assessment; PPV, Positive Predictive Value; NPV, Negative Predictive Value.

^*Kappa coefficient >0.6 is significant.