Table 2.

Risk factors and other worth mentioning features of uveal melanoma

Parameter	Distribution
Congenital risk factors	Light eye color, fair skin color, inability to tan and propensity to sunburn, oculodermal melanocytosis, cutaneous, iris and choroidal nevus, ancestry from northern latitudes
Main environmental risk factors	Welding, occupational cooking, sunlight exposure
Overall mortality rate	40–50% in 15 years
Metastases rate	50% of patients
Survival rate (month)
With liver metastases	4–6
Other metastases	19–28
Metastatic location (%)
Liver	89
Lung	29
Bone	17
Skin and subcutaneous tissue	12
Lymph nodes	11
Central nervous system	2
Predictive factors for metastatic disease	Basal tumor diameter, ciliary body involvement, extrascleral extension, epithelioid melanoma cytology, microvascular density