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. 2021 Jun 2;11:11645. doi: 10.1038/s41598-021-91113-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Phenome-wide association study of the V122I variant and 427 ICD10 diagnosis codes in the African ancestry UK Biobank population. The dotted gray line indicates a multiple comparison-corrected significance cutoff of p < 1.2 × 10^–4. ICD10 International Statistical Classification of Diseases and Related Health Problems, 10th Revision; V122I valine-to-isoleucine substitution at position 122.