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Attributable risk of common hATTR amyloidosis manifestations in the UK Biobank African ancestry population (n = 6062) due to the V122I variant.
| Diagnoses in V122I carriers (%) (n/N) | Population attributable risk to V122I variant (%) | |
|---|---|---|
| Polyneuropathy | 20.0 (5/25) | 16.7 |
| CTS | 7.5 (13/174) | 4.1 |
| Cardiomyopathy | 7.5 (3/40) | 2.4 |
| HF | 10.2 (10/98) | 6.5 |
| At least one common hATTR amyloidosis manifestation | 8.7 (27/311) | 5.5 |
