Figure 4.
Mitochondrial measures and IL-6 in high-grade epithelial ovarian carcinoma. (A) Pearson correlations between mitochondrial measures and IL-6 levels measured in ascites and plasma. Note the similar patterns of correlation between ascites and plasma, and the contrast in the associations between mtDNA-related measures (positive) and primary measures of mitochondrial content and respiratory chain function (negative). (B) Scatterplots of the correlations between ascites IL-6 levels and the mitochondrial health index (MHI), and (C) mtDNA density per mitochondrion (mtDNAcn/CS). n = 50–64 for ascites, 82–110 for plasma.