Figure 2.

Selective cytotoxicity of Oba01 under in vitro conditions

Jurkat E6-1, Jurkat, J.gamma1, Reh, A3, MT-4, TF-1, Kasumi-1, and Daudi cells were treated with increasing concentrations of Oba01, zaptuzumab, MMAE, and hertuzumab-MC-VC-PAB-MMAE (Ctl-ADC) for 72 h. Thereafter, the cell growth and viability were determined by a CellTiter-Glo luminescent cell viability assay according to the manufacturer’s instructions.