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. 2021 May 20;12:679430. doi: 10.3389/fneur.2021.679430

Table 3.

Comparison of the MRI manifestations of the pediatric and adult patients with MOG-EM.

Pediatric group Adult group P-valve
Brain MRI
    Abnormal 48.15% (13/27) 90% (18/20) 0.0028
    Subcortical white matter 40.74% (11/27) 45% (9/20) 0.7703
    Infratentorial lesion 18.52% (5/27) 30% (6/20) 0.5682
    Centrum semiovale 3.70% (1/27) 35% (7/20) 0.0151
    Periventricular 25.93% (7/27) 35% (7/20) 0.5012
    Deep gray matter 25.93% (7/27) 20% (4/20) 0.8997
    Corpus callosum 7.41% (2/27) 5% (1/20) 0.7875
Optic nerve MRI
    Abnormal 76.92% (20/26) 78.57% (11/14) 0.7811
    Bilateral involvement 61.54% (16/26) 14.29% (2/14) 0.0042
    Unilateral involvement 15.38% (4/26) 64.29% (9/14) 0.0052
Spinal cord MRI
    Abnormal 36.36% (8/22) 41.67% (5/12) 1.0000
    Cervicothoracic segments 36.36% (8/22) 41.67% (5/12) 1.0000
    Lumbosacral segments 4.55% (1/22) 0% (0/12) 1.0000
    ≥3 segments 18.18% (4/22) 25% (3/12) 0.6856