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. 2021 May 20;12:628041. doi: 10.3389/fgene.2021.628041

TABLE 2.

The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of differentially expressed genes in spleen tissues on ED18 of incubation, LNV and DNV treatments, and day 7 post-hatch, LPHV, DPHV, LIV, and DIV treatments, that were exposed to green monochromatic light during incubation, were subjected to the DAVID database for pathway enrichment analysis.

Group KEGG ID Pathway terms Fold enrichment Entrez IDs of genes
LNV vs. DNV gga00190 gga04620 gga03020 -Oxidative phosphorylation -Toll-like receptor signaling pathway -RNA polymerase 3.05 2.5 1.5 -PPA2, NDUFA5, NDUFS6, COX7C, UQCRFS1, NDUFB5 -NFKBIA, PIK3CG, TOLLIP, MAPK12, IRAK4 -POLR1D, POLR2F, POLR2D
LPHV vs. DPHV gga01100 gga03320 -Metabolic pathways -PPAR signaling pathway 14.3 2.9 -PNLIPRP1, PSPH, ALDOB, SIIL, PLA2G1B, ATP5A1W, CEL, FUT9, ADH1C, GATM, TCIRG1, HPD, PLA2G1BL, AMY2A, UGT1A1 -SCD, APOC3, FABP1
LIV vs. DIV gga01100 -Metabolic pathways 12.5 -PNLIPRP1, SIIL, PLA2G1B, CEL, PLA2G1BL, FUT9, AMY2A

All the pathways with a modified Fisher exact P-value < 0.05 and a threshold gene count of 2 were considered enriched.