Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 20;12:657636. doi: 10.3389/fgene.2021.657636

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Shi, He, Chen, Yin, Sha and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The mechanism of ND induced by acceleration aging. The brown gene is a biomarker of ND. The gray gene is the top MCMC marker of aging. The red gene is the top MCMC marker of each ND type. The pink gene is the network node with highest betweenness. The yellow arrow indicates the connection of Calcium homeostasis. The purple arrow represents a link to DNA damage repair response. The green arrow represents the link with the mitochondrial function. The brown arrow represents a link to oxidative stress. The black arrow indicates the connection with ubiquitin. The red arrow indicates the connection of the intracellular signal.