TABLE 4.
Descriptive statistics of the demographic, clinical, biological and genetic variables of subjects for each subtype
| Age (years) | Sex (M/F) | Education (years) | MMSE (raw score) | Aβ1-42 (positive/negative) | APOE-ε4 (carriers/ non carriers) | ||
|---|---|---|---|---|---|---|---|
| Training Set | Subtype 1 | 72.5 ± 7.2a | 48%/52%a | 15.9 ± 2.7a | 26.6 ± 2.6a | 72%/28%a | 48%/52% |
| Subtype 2 | 73.8 ± 6.7a | 84%/16%a,b | 16.4 ± 2.7a | 27.9 ± 2.0a,b | 53%/46%a,b | 44%/56% | |
| Subtype 3 | 74.8 ± 6.2 | 61%/39%b | 15.9 ± 3.0 | 26.5 ± 2.6b | 79%/21b | 42%/58% | |
| Test Set | Subtype 1 | 60 ± 24c | 41%/59%a | 8.5 ± 5.4a | 26.7 ± 3.3 | 3%/10% | 8%/14% |
| Subtype 2 | 63 ± 17b | 64%/36%a | 10.4 ± 5.6a | 27.4 ± 2.2b | 31%/15% | 24%/25% | |
| Subtype 3 | 74.4 ± 5.7c,b | 46%/54% | 7.9 ± 6.1 | 25.7 ± 4.7b | 15%/0% | 0%/15% |
Values marked with aindicate significant differences (p-value < 0.05) between Subtype 1 and Subtype 2 values in the same set; values marked with cindicate significant differences (p-value < 0.05) between Subtype 1 and Subtype 3 values in the same set; values marked with bindicate significant differences (p-value < 0.05) between Subtype 2 and Subtype 3 values in the same set.