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Schematic overview of our study design. Mouse samples consisted of adult male C57BL/6J from two independent cohorts (from Walker et al. 2018). We also utilized two human samples of adult males diagnosed with cocaine abuse or dependence (Bannon et al. 2014; Zhou et al. 2011), which we defined as cocaine use disorder (CUD). Mouse and human samples used analogous brain regions (hippocampus and ventral tegmental area (VTA)/midbrain).
