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. 2021 May 27;13(5):557–570. doi: 10.4254/wjh.v13.i5.557

Table 2.

Main indicators of patients with cirrhosis with severe and non-severe dysbiosis


Severe dysbiosis (n = 24)
Non-severe dysbiosis (n = 24)
P value
Age, yr 51.5 (42.0-59.0) 50.0 (35.0-57.5) 0.392
Body mass index, kg/m2 24.6 (22.8-27.7) 24.2 (22.7-27.7) 0.837
Male/female 12/12 11/13 0.500
Etiology of cirrhosis: Alcohol 9 9 0.617
Autoimmune 2 7 0.068
HBV 7 2 0.068
HCV 5 3 0.350
Cryptogenic 1 3 0.304
Child–Turcotte–Pugh score 9 (8-10) 7 (6-9) 0.047
Death 13 3 0.001
Death within the first year of follow-up 5 2 0.092
Death during the following years of follow-up 8 1 0.002
Esophageal varices (present/absent) 20/4 18/6 0.477
Hepatic encephalopathy (overt/minimal/absent) 11/9/4 6/11/7 0.288
Number connection test, seconds 87 (65-118) 79 (59-92) 0.248
Ascites (present/absent) 16/8 11/13 0.122
Spontaneous bacterial peritonitis (present/absent) 0/24 0/24 1.000
Red blood cells, 1012 cell/L 3.8 (3.4-4.0) 3.9 (3.6-4.5) 0.370
White blood cells, 109 cell/L 3.8 (2.7-5.3) 3.8 (3.1-5.2) 0.628
Platelets, 109 cell/L 87 (55-120) 76 (60-108) 0.860
Serum total protein, g/L 70 (61-76) 73 (64-78) 0.599
Serum albumin, g/L 31 (28-37) 38 (34-41) 0.009
Serum total bilirubin, μmol/L 47 (31-62) 31 (24-63) 0.375
Prothrombin index (Quick test), % 58 (48-67) 64 (54-71) 0.239
Creatinine, mg/dL 0.69 (0.53-0.87) 0.73 (0.66-0.90) 0.187
Serum sodium, mmol/L 141 (139-144) 141 (138-143) 0.795
Serum potassium, mmol/L 4.3 (4.0-4.7) 4.3 (4.1-4.7) 0.844
Serum glucose, mmol/L 5.1 (4.7-5.6) 5.3 (4.7-6.0) 0.260
Alanine aminotransferase, U/L 36 (25-72) 37 (23-60) 0.804
Aspartate aminotransferase, U/L 54 (41-98) 40 (26-67) 0.219
Gamma glutamyl transferase, U/L 77 (40-148) 76 (36-131) 0.621
Alkaline phosphatase, U/L 221 (188-340) 222 (166-298) 0.542
Cholinesterase, kU/L 2.7 (1.9-3.7) 4.0 (3.6-4.5) 0.031
C-reactive protein, mg/L 10.1 (2.1-16.1) 2.1 (0.3-8.9) 0.032
Splenic length, cm 15.4 (14.0-17.6) 16.1 (13.3-19.2) 0.841

HBV: Hepatitis B virus; HCV: Hepatitis C virus.