Table. Patient Characteristics in Participants With and Without P/LP Gene Variants.
| Characteristic | Median (IQR) | P value | ||||
|---|---|---|---|---|---|---|
| With P/LP variant (n = 76) | Without P/LP variant (n = 337) | |||||
| Age, y | 39.0 (28.0-48.0) | 41.2 (31.0-48.0) | .22 | |||
| Sex, No. (%) | ||||||
| Women | 29 (38.2) | 125 (37.1) | .52 | |||
| Men | 47 (61.8) | 212 (62.9) | ||||
| African American, No. (%) | 32 (42.1) | 176 (52.2) | .47 | |||
| Body/heart dimensions | Women (n = 29) | Men (n = 47) | Women (n = 125) | Men (n = 212) | P value for women | P value for men |
| Body height, cm | 165.1 (162.6-174.0) | 177.8 (170.2-180.3) | 167.6 (162.6-172.1) | 177.8 (172.7-184.8) | .82 | .37 |
| Body weight, kg | 74.4 (62.8-108.4) | 81.7 (72.1-91.2) | 80.3 (62.6-96.6) | 83.0 (71.2-97.8) | .96 | .49 |
| BMI | 27.0 (22.0-36.2) | 26.2 (23.0-29.0) | 29.0 (23.3-34.6) | 26.5 (22.6-30.2) | .98 | .70 |
| Body surface area, m2 | 1.72 (1.56-2.11) | 1.87 (1.74-1.98) | 1.80 (1.60-1.96) | 1.90 (1.73-2.07) | .87 | .48 |
| Heart weight, g | 350.0 (300.0-420.0) | 400.0 (372.0-450) | 350.0 (300.0-420.0) | 430.0 (380.0-466) | .81 | .10 |
| LV diameter, mm | 35.0 (15.0-39.5) | 30.0 (25.0-38.0) | 35.0 (28.5-40.0) | 35.0 (30.0-40.0) | .99 | .39 |
| LV free wall thickness, mm | 13.0 (12.0-15.0) | 14.0 (12.0-15.0) | 12.0 (10.0-14.0) | 14.0 (12.0-15.0) | .06 | .18 |
| Septum thickness, mm | 13.0 (12.0-15.0) | 14.0 (11.0-16.0) | 14.0 (12.0-15.0) | 15.0 (14.0-17.0) | .26 | .73 |
| RV thickness, mm | 4.0 (4.0-5.0) | 5.0 (4.0-5.5) | 4.0 (4.0-5.0) | 5.0 (4.0-5.0) | .56 | .30 |
| Septum to free wall ratio | 1.08 (1.00-1.18) | 1.09 (1.06-1.18) | 1.13 (1.10-1.20) | 1.08 (1.00-1.19) | .16 | .19 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); IQR, interquartile range; LV, left ventricle; P/LP, pathogenic/likely pathogenic; RV, right ventricle.