Table 2. List of MHC-I Binding Epitopes Predicted by the NetMHCcons 1.1 Server with Threshold: Threshold for Strong Binding Peptide 0.50% (% Rank)a.
s. no. | protein | position | allele | peptide | 1-log50k(aff)* | affinity (nM)# | % rank | class I immunogenicity score |
---|---|---|---|---|---|---|---|---|
1. | GapA | 984 | HLA-B40:06 | QEFTGFDAL | 0.417 | 549.34 | 0.50 | 0.26184 |
HLA-B41:04 | 0.582 | 92.19 | 0.17 | |||||
HLA-B41:03 | 0.666 | 37.11 | 0.12 | |||||
2. | PlpA | 817 | HLA-B40:06 | YEYPEYEEI | 0.427 | 492.48 | 0.40 | 0.22466 |
HLA-B41:03 | 0.601 | 74.57 | 0.50 | |||||
3. | Hlp3 | 907 | HLA-B41:03 | QELLRYNVI | 0.602 | 74.16 | 0.50 | 0.05082 |
HLA-B41:04 | 0.588 | 86.16 | 0.17 | |||||
4. | CrmA | 769 | HLA-B40:06 | NEIGVILPL | 0.518 | 184.51 | 0.12 | 0.22694 |
HLA-B41:03 | 0.693 | 27.86 | 0.05 | |||||
HLA-B41:04 | 0.594 | 80.45 | 0.15 |
*Prediction score, #affinity as the IC50 value in nanometer.