Figure 1.

HLA-I peptidome and whole-proteome measurements in SARS-CoV-2-infected cells

(A) Schematic of the experiment and the antigen presentation pathway.

(B) Population frequency of the 9 endogenous HLA-I alleles expressed in A549 and HEK293T cells.

(C) Length distribution of HLA peptides in infected and naive cells.

(D) Motif of 9-mer sequences identified in infected and naive cells.

(E) Fraction of observed peptides assigned to alleles using HLAthena prediction (%rank cutoff < 0.5) for the immunopeptidome of infected and uninfected cells.

See also Figures S1 and S2 and Table S1.