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. 2021 Jun 3;184(15):3962–3980.e17. doi: 10.1016/j.cell.2021.05.046

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Figure S5 — Population coverage estimates of LC-MS/MS-identified SARS-CoV-2 HLA-I peptides, related to Figure 7

HLAthena predictions for 92 HLA-I alleles using percentile rank cutoff values of 0.1, 0.5, 1, and 2% were used to show the number of alleles and estimated coverage for each LC-MS/MS-observed SARS-CoV-2 peptides across (A) AFA, (B) API, (C) EUR, (D) HIS, and (E) USA populations. Alleles are colored and ordered according to loci and the corresponding population frequency (high to low color intensity). Peptides are ordered according to their estimated coverage at %rank cutoff of 0.5.