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. 2021 Jun 3;184(15):3962–3980.e17. doi: 10.1016/j.cell.2021.05.046

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© 2021 The Authors

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Figure S6 — HLA-I peptide sequences in B.1.1.7, P.1, and B.1.351 SARS-CoV-2 variants, related to Figure 6

(A) The sequence of the HLA-I peptides detected in our study were used as tblastn queries against a database containing early representative genomes of SARS-CoV-2 lineages with the pango designations B.1.1.7 (29 genomes), P.1 (14 genomes), and B.1.351 (23 genomes); see GISAID acknowledgment table for accessions (Table S8). Identity scores for each peptide in each variant are shown in the heatmap. (B,C) Mutations in the S.iORF1/2 region of B.1.351 (B) and B.1.1.7 (C) variants in comparison to the SARS-CoV-2 RefSeq sequence NC_045512.2 isolated from Wuhan. The position of the three HLA-I peptides is indicated.