Table 3.

Year to year comparison of hour–hour insulin sensitivity variability (%∆S_I). As comparisons are symmetric, the upper triangle in presents the median (95% CI) difference in medians (50th percentile) between years, while the lower triangle gives the median (95% CI) difference at the upper quartile (75th percentile).

	2011	2012	2013	2014	2015	2016	2017	2018
2011		0.0 (−3.5 to 3.6) ⇔	0.4 (−3.5 to 4.0) ⇔	1.2 (−2.2 to 4.4) ⇔	1.4 (−2.1 to 4.8) ⇔	1.4 (−1.9 to 4.5) ⇔	0.6 (−2.7 to 3.8) ⇔	0.9 (−2.3 to 4.1) ⇔
2012	−2.8 (−8.2 to 3.3) ⇔ a		0.4 (−1.4 to 2.1) ⇔	1.2 (−0.6 to 2.7) ⇔	1.4 (−0.3 to 3.2) ⇔	1.4 (−0.6 to 3.0) ⇔	0.6 (−1.2 to 2.4) ⇔	0.9 (−1.1 to 2.9) ⇔
2013	−4.2 (−9.9 to 2.3) ⇔a,b	−1.3 (−4.3 to 1.6) ⇔ a		0.8 (−0.9 to 2.3) ⇔	1.0 (−0.8 to 2.8) ⇔	1.0 (−1.1 to 2.8) ⇔	0.2 (−1.7 to 2.2) ⇔	0.5 (−1.6 to 2.9) ⇔
2014	2.2 (−2.4 to 7.7) ⇔ a	5.1 (2.2 to 7.6) ⇔ a	6.4 (3.6 to 8.9) ⇔ a		0.2 (−1.4 to 1.8) ⇔	0.1 (−1.6 to 1.8) ⇔	−0.6 (−2.2 to 1.3) ⇔	−0.3 (−2.2 to 1.8) ⇔
2015	−0.3 (−6.2 to 5.4) ⇔ a	2.6 (−0.3 to 5.3) ⇔a,b	3.9 (0.9 to 6.7) ⇔ a	−2.5 (−4.9 to −0.1) ⇔ a		−0.1 (−1.8 to 1.7) ⇔	−0.8 (−2.6 to 1.0) ⇔	−0.5 (−2.5 to 1.4) ⇔
2016	0.5 (−5.6 to 6.7) ⇔ a	3.4 (0.2 to 6.5) ⇔ a,b	4.7 (1.5 to 7.8) ⇔ a	−1.7 (−4.4 to 1.1) ⇔ a	0.8 (−2.2 to 3.8) ⇔ a		−0.8 (−2.4 to 1.16) ⇔	−0.5 (−2.4 to 1.6) ⇔
2017	−0.6 (−7.1 to 5.1) ⇔ a	2.3 (−1.1 to 5.6) ⇔a,b	3.6 (−0.1 to 7.0) ⇔ a	−2.8 (−5.7 to −0.0) ⇔ a	−0.3 (−3.5 to 2.5) ⇔a,b	−1.1 (−4.4 to 2.1) ⇔ a		0.3 (−1.6 to 2.2) ⇔
2018	0.6 (−4.7 to −6.5) ⇔ a	3.5 (0.2−6.8) ⇔ a	4.8 (1.1–8.1) ⇔ a	−1.6 (−4.5 to 1.4) ⇔a,b	0.9 (−2.3 to 4.5) ⇔ a	0.1 (−3.0 to 3.3) ⇔ a	1.2 (−2.1 to 4.8) ⇔ a

⇔ shows equivalent to %∆SI < +/−15%, where the median and IQR in Figure 3 are equivalent across all years. Bolded values are independently statistically different to p < 0.0018.

^aAlso equivalent at the 80th percentile.

^bAlso equivalent at the 90th percentile.

CI, confidence interval; SI, insulin sensitivity.