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. Author manuscript; available in PMC: 2022 May 17.
Published in final edited form as: Dev Cell. 2021 Apr 22;56(10):1394–1407. doi: 10.1016/j.devcel.2021.03.034

Figure 3. Pro-longevity signaling pathways regulating lipid metabolism.

Figure 3.

Molecular characterization of conserved pro-longevity signaling mechanisms, including IIS, mTOR signaling, and germline endocrine signals, have uncovered interesting mechanistic links between lipid metabolism and longevity. In C. elegans, multiple transcription factors/mediators and nuclear receptors act in these pathways to regulate different lipid metabolic processes.