Table 2.

Compliance with the 2009 Belarusian national gonorrhoea guideline [45] in Minsk (749 patients, 2013–2018) and Mogilev (903 patients, 2010–2019), Belarus

Prescribed antimicrobials	Minsk No. (%, 95 CI)	Mogilev No. (%, 95 CI)
Recommended first-line treatment [45]
CRO 1 g × 1 IM (uncomplicated gonorrhoea) or CRO 1 g × 1 IM or IV every 24 h, 7 days (complicated gonorrhoea)a	354 (47.3, 43.7–51.0)	508 (56.3, 53.0–59.6)
Alternative treatment [45]
CFM 400 mg × 1 orally	5 (0.7, 0.2–1.6)	0
OFX 400 mg × 1 orally	26 (3.5, 2.3–5.1)	123 (13.6, 11.4–16.0)
Non-compliant treatment
Non-compliant antimicrobials or doses given, generally higher than recommended	364 (48.6, 45.0–52.3)b	272 (30.1, 27.1–33.2)c

No. Number, CI Confidence interval, CRO Ceftriaxone, IM Intramuscularly, IV Intravenously, CFM Cefixime, OFX Ofloxacin

^aFrequently, additional antimicrobials were given to treat other non-viral STIs, which had been confirmed or not excluded by appropriate laboratory diagnostics. These included doxycycline, other tetracyclines, different macrolides, fluoroquinolones, oral cephalosporins, penicillins, and nitroimidazoles

^bMore than 1 g of ceftriaxone was quite often given; approximately 10% of the patients received benzylpenicillin, about 5% a tetracycline/macrolide regimen, and one (0.1%) patient was given rifampicin

^cMore than 1 g of ceftriaxone was somewhat frequently given. A benzylpenicillin regimen was rarely given, and for a few patients, > 400 mg ofloxacin or a tetracycline/macrolide regimen was administered