Table 1.
Coagulation-related proteins in PCOS and control women
| Control (n = 68) | PCOS (n = 99) | p value | |
|---|---|---|---|
| Procoagulant | |||
| Fibrinogen | 169,317 (2913) | 181,362 (2602 | 0.003 |
| D-dimer | 12,770 (196) | 14,311 (208) | < 0.0001 |
| Coagulation factor Xa | 5536 (103) | 5811 (87) | 0.043 |
| von Willebrand Factor | 13,389 (680) | 23,629 (4449) | 0.0598 |
| Coagulation factor XI | 1801 (33) | 1830 (31) | 0.54 |
| Prothrombin | 164,626 (2344) | 159,685 (1588) | 0.07 |
| Integrin alpha1:beta1 | 558 (32) | 691 (40) | 0.017 |
| Complement factor I | 41,949 (833) | 47,885 (762) | < 0.0001 |
| Coagulation factor VII | 569 (27) | 581 (11) | 0.65 |
| P-selectin | 12,776 (545) | 14,259 (372) | 0.02 |
| Plasminogen activator inhibitor 1 | 1495 (134) | 2521 (185) | < 0.0001 |
| Alpha-2 antiplasmin | 1979 (30) | 1950 (17) | 0.37 |
| Plasma kallikrein | 22,653 (517) | 24,954 (435) | 0.0009 |
| Fibrinogen gamma chain | 57,240 (1007) | 65,382 (1146) | < 0.0001 |
| Fibronectin fragment 3 | 3287 (112) | 4702 (540) | 0.03 |
| Fibronectin fragment 4 | 68,907 (1699) | 84,082 (4181) | 0.004 |
| Fibronectin | 16,170 (808) | 27,686 (3759) | 0.013 |
| Tissue factor | 2051 (551) | 1872 (362) | 0.78 |
| Anticoagulant | |||
| Antithrombin | 125,181 (1849) | 118,218 (1354) | 0.002 |
| PECAM1 | 795 (9) | 834 (13) | 0.03 |
| Tissue type plasminogen activator | 469 (22) | 627 (21) | < 0.0001 |
| Plasminogen | 4559 (78) | 4547 (80) | 0.92 |
| Plasmin | 636 (33) | 660 (27) | 0.56 |
| Protein S | 3971 (71) | 4385 (88) | 0.0008 |
| Heparin cofactor II | 3824 (77) | 4197 (79) | 0.0014 |
PECAM1 platelet endothelial cell adhesion molecule 1
Bolded p-values indicate significance at level of p < 0.05