Table 3.
Linear associations for MS components related to head and neck cancer risk
| MS components | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| Waist circumferencea | 1.43[1.34, 1.53] | <0.001 | 1.16[1.07, 1.25] | <0.001 | 1.09[1.01, 1.18] | 0.032 |
| Waist circumference (male) | 1.19[1.10, 1.28] | <0.001 | 1.19[1.10, 1.28] | <0.001 | 1.10[1.02, 1.20] | 0.019 |
| Waist circumference (female)b | 0.98[0.85, 1.13] | 0.788 | 0.98[0.85, 1.13] | 0.796 | 0.95[0.82, 1.10] | 0.490 |
| HDL-Ca | 0.78[0.72, 0.84] | <0.001 | 1.02[0.93, 1.11] | 0.723 | 1.07[0.98, 1.17] | 0.098 |
| HDL-C (male)b | 1.01[0.93, 1.10] | 0.801 | 1.01[0.93, 1.10] | 0.783 | 1.05[0.97, 1.15] | 0.243 |
| HDL-C (female)b | 1.02[0.87, 1.18] | 0.830 | 1.02[0.88, 1.18] | 0.821 | 1.08[0.92, 1.27] | 0.329 |
| Blood glucoseb | 1.09[1.03, 1.15] | 0.002 | 1.07[1.01, 1.13] | 0.018 | 1.06[1.01, 1.12] | 0.032 |
| Diastolic blood pressureb | 1.07[1.00, 1.05] | 0.043 | 0.99[0.92, 1.06] | 0.716 | 0.99[0.93, 1.07] | 0.848 |
| Systolic blood pressure | 1.09[1.01, 1.17] | 0.018 | 1.03[0.96, 1.11] | 0.415 | 1.03[0.96, 1.10] | 0.451 |
| Triglycerides (mmol/L) | 1.12[1.05, 1.20] | <0.001 | 1.03[0.97, 1.11] | 0.339 | 0.97[0.91, 1.04] | 0.407 |
Model 1: unadjusted
Model 2: age and gender-stratified model
Model 3: additionally adjusted for education, ethnic, index of multiple deprivation, alcohol consumption, smoking status, physical activity, fruit and vegetable intake, NASIDS use and CRP
aMS component with sex-specific definition
bU-shaped association MS components related to head and neck cancer risk in non-linear spline models